Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | set03_absentNotch_versus_normalThy |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | NCI_IL2-MEDIATED SIGNALING EVENTS |
| Enrichment Score (ES) | -0.5490874 |
| Normalized Enrichment Score (NES) | -1.8805369 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.088882156 |
| FWER p-Value | 0.674 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GRB2 | 736 | 3.346 | -0.0260 | No | ||
| 2 | RPS6 | 1042 | 2.877 | -0.0306 | No | ||
| 3 | PRKCZ | 1203 | 2.659 | -0.0282 | No | ||
| 4 | STAT5A | 1251 | 2.601 | -0.0200 | No | ||
| 5 | E2F1 | 1260 | 2.582 | -0.0098 | No | ||
| 6 | MYC | 1312 | 2.533 | -0.0021 | No | ||
| 7 | TRAF6 | 1541 | 2.310 | -0.0049 | No | ||
| 8 | PPP2R5D | 1800 | 2.119 | -0.0100 | No | ||
| 9 | MAPKAPK2 | 2095 | 1.954 | -0.0179 | No | ||
| 10 | RAN | 2127 | 1.938 | -0.0115 | No | ||
| 11 | HSP90AA1 | 2483 | 1.761 | -0.0234 | No | ||
| 12 | SGMS1 | 2779 | 1.631 | -0.0326 | No | ||
| 13 | MAP2K2 | 3298 | 1.440 | -0.0547 | No | ||
| 14 | MAPK8 | 3997 | 1.205 | -0.0874 | No | ||
| 15 | CYLD | 4057 | 1.190 | -0.0857 | No | ||
| 16 | CALM1 | 4140 | 1.168 | -0.0853 | No | ||
| 17 | RPS6KB1 | 4288 | 1.133 | -0.0886 | No | ||
| 18 | KRAS | 4401 | 1.100 | -0.0901 | No | ||
| 19 | NRAS | 4773 | 1.011 | -0.1060 | No | ||
| 20 | GAB2 | 5106 | 0.933 | -0.1200 | No | ||
| 21 | RAF1 | 5344 | 0.875 | -0.1292 | No | ||
| 22 | FRAP1 | 5621 | 0.816 | -0.1408 | No | ||
| 23 | UBE2D3 | 5759 | 0.787 | -0.1449 | No | ||
| 24 | XPO1 | 5864 | 0.766 | -0.1474 | No | ||
| 25 | RAC1 | 5946 | 0.749 | -0.1487 | No | ||
| 26 | IL4 | 6034 | 0.730 | -0.1504 | No | ||
| 27 | PIK3R1 | 6233 | 0.693 | -0.1582 | No | ||
| 28 | PRKCE | 6499 | 0.633 | -0.1699 | No | ||
| 29 | NFKB1 | 6645 | 0.606 | -0.1752 | No | ||
| 30 | INSL3 | 6760 | 0.579 | -0.1790 | No | ||
| 31 | IL2 | 6830 | 0.565 | -0.1804 | No | ||
| 32 | CHUK | 6859 | 0.560 | -0.1796 | No | ||
| 33 | AKT1 | 6874 | 0.557 | -0.1780 | No | ||
| 34 | CCNA2 | 6998 | 0.530 | -0.1825 | No | ||
| 35 | CDK6 | 7188 | 0.494 | -0.1907 | No | ||
| 36 | TNF | 8047 | 0.328 | -0.2357 | No | ||
| 37 | ARRB2 | 8399 | 0.264 | -0.2536 | No | ||
| 38 | BCL3 | 8868 | 0.178 | -0.2781 | No | ||
| 39 | HRAS | 9039 | 0.147 | -0.2867 | No | ||
| 40 | MAP2K1 | 9344 | 0.087 | -0.3028 | No | ||
| 41 | CALM2 | 9554 | 0.043 | -0.3139 | No | ||
| 42 | MALT1 | 10394 | -0.146 | -0.3586 | No | ||
| 43 | PRKCA | 10410 | -0.150 | -0.3588 | No | ||
| 44 | JUN | 10501 | -0.169 | -0.3630 | No | ||
| 45 | SOS1 | 10560 | -0.179 | -0.3654 | No | ||
| 46 | FOS | 11102 | -0.290 | -0.3934 | No | ||
| 47 | TERT | 11462 | -0.365 | -0.4113 | No | ||
| 48 | REL | 11773 | -0.433 | -0.4263 | No | ||
| 49 | BIRC2 | 12309 | -0.559 | -0.4529 | No | ||
| 50 | SP1 | 12543 | -0.615 | -0.4629 | No | ||
| 51 | FBXW11 | 12567 | -0.619 | -0.4616 | No | ||
| 52 | IFNG | 12581 | -0.623 | -0.4597 | No | ||
| 53 | JAK3 | 12893 | -0.700 | -0.4737 | No | ||
| 54 | JAK1 | 13010 | -0.731 | -0.4769 | No | ||
| 55 | ELF1 | 13220 | -0.790 | -0.4849 | No | ||
| 56 | SRC | 13221 | -0.790 | -0.4817 | No | ||
| 57 | SOCS3 | 13595 | -0.902 | -0.4981 | No | ||
| 58 | PRF1 | 13726 | -0.939 | -0.5013 | No | ||
| 59 | MAPK3 | 13948 | -1.009 | -0.5090 | No | ||
| 60 | FOXO3 | 14022 | -1.039 | -0.5087 | No | ||
| 61 | SYK | 14216 | -1.106 | -0.5145 | No | ||
| 62 | PIK3CA | 14498 | -1.205 | -0.5247 | No | ||
| 63 | MAPK14 | 14531 | -1.214 | -0.5215 | No | ||
| 64 | RASA1 | 14704 | -1.279 | -0.5255 | No | ||
| 65 | IKBKB | 14715 | -1.283 | -0.5207 | No | ||
| 66 | IRS1 | 15115 | -1.449 | -0.5363 | No | ||
| 67 | SMPD1 | 15130 | -1.456 | -0.5310 | No | ||
| 68 | PTPN11 | 15185 | -1.479 | -0.5278 | No | ||
| 69 | MAPK1 | 15209 | -1.490 | -0.5229 | No | ||
| 70 | ERC1 | 15304 | -1.543 | -0.5216 | No | ||
| 71 | CDK2 | 15515 | -1.650 | -0.5262 | No | ||
| 72 | NOD2 | 15778 | -1.802 | -0.5329 | No | ||
| 73 | STAT5B | 15983 | -1.926 | -0.5360 | No | ||
| 74 | STAM2 | 16227 | -2.118 | -0.5403 | Yes | ||
| 75 | ATM | 16233 | -2.123 | -0.5318 | Yes | ||
| 76 | STAM | 16301 | -2.185 | -0.5264 | Yes | ||
| 77 | IL2RA | 16308 | -2.190 | -0.5177 | Yes | ||
| 78 | SHC1 | 16333 | -2.217 | -0.5099 | Yes | ||
| 79 | DOK2 | 16383 | -2.256 | -0.5032 | Yes | ||
| 80 | MAP3K14 | 16495 | -2.360 | -0.4994 | Yes | ||
| 81 | IL2RB | 16526 | -2.388 | -0.4912 | Yes | ||
| 82 | RELB | 16614 | -2.472 | -0.4857 | Yes | ||
| 83 | NFKBIA | 16685 | -2.540 | -0.4790 | Yes | ||
| 84 | CALM3 | 16720 | -2.583 | -0.4702 | Yes | ||
| 85 | CCND3 | 16825 | -2.709 | -0.4646 | Yes | ||
| 86 | MAPK9 | 16893 | -2.804 | -0.4566 | Yes | ||
| 87 | NFKB2 | 16979 | -2.902 | -0.4492 | Yes | ||
| 88 | UGCG | 17006 | -2.936 | -0.4385 | Yes | ||
| 89 | RIPK2 | 17205 | -3.242 | -0.4358 | Yes | ||
| 90 | MYB | 17211 | -3.247 | -0.4227 | Yes | ||
| 91 | LCK | 17279 | -3.355 | -0.4124 | Yes | ||
| 92 | SOCS1 | 17323 | -3.435 | -0.4006 | Yes | ||
| 93 | SOCS2 | 17411 | -3.609 | -0.3904 | Yes | ||
| 94 | BCL2L1 | 17452 | -3.694 | -0.3773 | Yes | ||
| 95 | RELA | 17490 | -3.802 | -0.3636 | Yes | ||
| 96 | BCL10 | 17534 | -3.900 | -0.3498 | Yes | ||
| 97 | CCND2 | 17556 | -3.932 | -0.3347 | Yes | ||
| 98 | FASLG | 17668 | -4.176 | -0.3234 | Yes | ||
| 99 | MAPK11 | 17757 | -4.401 | -0.3100 | Yes | ||
| 100 | LTA | 17854 | -4.683 | -0.2958 | Yes | ||
| 101 | IL2RG | 17859 | -4.705 | -0.2766 | Yes | ||
| 102 | STAT3 | 17907 | -4.850 | -0.2591 | Yes | ||
| 103 | FOXP3 | 17920 | -4.888 | -0.2396 | Yes | ||
| 104 | IKBKG | 17938 | -4.921 | -0.2202 | Yes | ||
| 105 | FYN | 18056 | -5.334 | -0.2045 | Yes | ||
| 106 | RHOA | 18189 | -5.967 | -0.1870 | Yes | ||
| 107 | TNFRSF1A | 18237 | -6.230 | -0.1638 | Yes | ||
| 108 | TNFAIP3 | 18342 | -7.081 | -0.1401 | Yes | ||
| 109 | CISH | 18418 | -7.783 | -0.1120 | Yes | ||
| 110 | STAT1 | 18476 | -8.708 | -0.0792 | Yes | ||
| 111 | PTK2B | 18534 | -10.458 | -0.0390 | Yes | ||
| 112 | BCL2 | 18536 | -10.511 | 0.0043 | Yes |
